Confirmatory validation of the Mesothelioma Psychological Distress Tool—Patients: A brief patient‐reported outcome measure assessing psychological distress in malignant mesothelioma patients

Author:

Bonafede Michela1ORCID,Franzoi Isabella Giulia2ORCID,Sauta Maria Domenica2,Marinaccio Alessandro1,Mensi Carolina3ORCID,Rugarli Sabrina3,Migliore Enrica4,Cozzi Ilaria5,Cavone Domenica6,Vimercati Luigi6,Grosso Federica7,Bertolotti Marinella8,Raimondi Giulia29,Innamorati Marco10,Granieri Antonella2ORCID

Affiliation:

1. Occupational and Environmental Medicine, Epidemiology and Hygiene Department Italian Workers' Compensation Authority (INAIL) Rome Italy

2. Department of Psychology University of Turin Turin Italy

3. COR Lombardy Occupational Health Unit Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico of Milan Milan Italy

4. COR Piedmont Unit of Cancer Epidemiology AOU Città della Salute e della Scienza di Torino CPO Piedmont and University of Turin Turin Italy

5. Department of Epidemiology COR Lazio Lazio Regional Health Service Local Health Unit 1 Rome Italy

6. Department of Interdisciplinary Medicine Section of Occupational Medicine “B. Ramazzini” Regional Operating Center of Puglia (COR Puglia) University of Bari Bari Italy

7. Mesothelioma and Rare Cancers Unit Azienda Ospedaliera SS Antonio e Biagio e Cesare Arrigo Alessandria Italy

8. Research Training Innovation Infrastructure Research and Innovation Department (DAIRI) AO SS Antonio e Biagio e Cesare Arrigo Alessandria Italy

9. Clinical Epidemiology Unit Istituto Dermopatico dell’Immacolata IDI‐IRCCS Rome Italy

10. Department of Human Sciences European University of Rome Roma Italy

Abstract

AbstractObjectivePsychological suffering in patients with Malignant Mesothelioma (MM) is different from the one experienced by patients with other cancers due to its occupational or environmental etiology and its peculiar symptomatology and prognosis (i.e., poor prognosis, reduced effectiveness of the therapies, poor quality of residual life, and advanced age at the time of diagnosis). Therefore, the Mesothelioma Psychological Distress Tool‐Patients (MPDT‐P) has been developed to evaluate the specific profile of psychological suffering in this population. This paper describes the item selection, factor analysis, and psychometric evaluation of the revised MPDT‐P.MethodsThe analyses of the current work aimed to confirm the factorial structure found in the first version of the MPDT‐P. In the case of nonfit, it aimed to find an alternative structure and causes of nonfit in the model. The search for the fit of the factorial model was conducted using a Bayesian approach.ResultsThe two‐factor model reported in the first version of the instrument did not fit the data. Confirmatory Bayesian analyses showed adequate fit for the three‐factor solution. Based on the content of the items, we labeled the factors as dysfunctional emotions, claims for justice, and anxieties about the future.ConclusionsIntegrating the MPDT‐P into clinical practice could help clinicians gain insight into the specific suffering related to MM and investigate potential differences related to different occupational and environmental exposure contexts.

Funder

Istituto Nazionale per l'Assicurazione Contro Gli Infortuni sul Lavoro

Publisher

Wiley

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