MicroRNA-506 promotes primary biliary cholangitis-like features in cholangiocytes and immune activation

Author:

Erice Oihane1,Munoz-Garrido Patricia12,Vaquero Javier34,Perugorria Maria J.125,Fernandez-Barrena Maite G.26,Saez Elena6,Santos-Laso Alvaro1,Arbelaiz Ander1,Jimenez-Agüero Raul1,Fernandez-Irigoyen Joaquin7,Santamaria Enrique7,Torrano Verónica89,Carracedo Arkaitz58910,Ananthanarayanan Meenakshisundaram11,Marzioni Marco12,Prieto Jesus26,Beuers Ulrich13,Oude Elferink Ronald P.13,LaRusso Nicholas F.14,Bujanda Luis12,Marin Jose J.G.23,Banales Jesus M.125

Affiliation:

1. Department of Liver and Gastrointestinal Diseases, Biodonostia Research Institute-Donostia University Hospital; University of the Basque Country (UPV/EHU); San Sebastian Spain

2. National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd); Carlos III National Institute of Health; Madrid Spain

3. Experimental Hepatology and Drug Targeting (HEVEFARM), Biomedical Research Institute of Salamanca (IBSAL); University of Salamanca; Salamanca Spain

4. Sorbonne Universités, UPMC Université Paris 06, INSERM, Saint-Antoine Research Center, Paris, and Fondation ARC; Villejuif France

5. IKERBASQUE, Basque Foundation for Science; Bilbao Spain

6. Division of Hepatology; CIMA of the University of Navarra; Pamplona Spain

7. Proteored-ISCIII, Proteomics Unit, Navarrabiomed, Navarra Health Department; Public University of Navarra, Navarra Institute for Health Research (IdiSNA); Pamplona Spain

8. CIC bioGUNE, Bizkaia Technology Park; Derio Bizkaia Spain

9. CIBERONC

10. Biochemistry and Molecular Biology Department; University of the Basque Country (UPV/EHU); Bilbao Spain

11. Liver Center; Yale University School of Medicine; New Haven CT

12. Department of Gastroenterology; Università Politecnica delle Marche; Ancona Italy

13. Department of Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, Academic Medical Centre; University of Amsterdam; Amsterdam The Netherlands

14. Division of Gastroenterology and Hepatology; Mayo Clinic; Rochester MN

Funder

Spanish Ministries of Economy and Competitiveness

Instituto de Salud Carlos III

Junta de Castilla y Leon

Diputación Foral Gipuzkoa

Departments of Industry, Tourism, Trade and Health of the Basque Country

Basque Foundation for Innovation and Health Research: EiTB Maratoia

National Institutes of Health

Asociación Española Contra el Cancer

Basque Government

Fundación Vasca de Innovación e Investigación Sanitarias

Department of Health of the Basque Government

AECC-Bizkaia

Basque Department of Industry, Tourism and Trade (Etortek)

FERO VIII

BBVA Foundation

MINECO

European Research Council

Publisher

Wiley

Subject

Hepatology

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