Exploring the Use of Serum‐Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Hepatic Cytochromes P450 and Organic Anion Transporting Polypeptides-Reference-Cited by-同舟云学术

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Exploring the Use of Serum‐Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Hepatic Cytochromes P450 and Organic Anion Transporting Polypeptides

Published:2021-04-18 Issue:1 Volume:110 Page:248-258
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Rodrigues A. David¹,Dyk Madelé²,Sorich Michael J.²,Fahmy Alia²,Useckaite Zivile²,Newman Lauren A.²,Kapetas Asha J.²,Mounzer Reham²,Wood Linda S.³,Johnson Jillian G.³,Rowland Andrew²

Affiliation:

1. ADME Sciences, Medicine Design Worldwide Research & Development Pfizer Inc. Groton Connecticut USA

2. College of Medicine and Public Health Flinders University Adelaide South Australia Australia

3. Pharmacogenomics, Precision Medicine Worldwide Research & Development Pfizer Inc. Groton Connecticut USA

Funder

Cancer Council South Australia

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2244

Reference49 articles.

1. Clinically important pharmacokinetic drug-drug interactions: role of cytochrome P450 enzymes

2. Clinical Importance of OATP1B1 and OATP1B3 in DrugDrug Interactions

3. From Endogenous Compounds as Biomarkers to Plasma‐Derived Nanovesicles as Liquid Biopsy; Has the Golden Age of Translational Pharmacokinetics‐Absorption, Distribution, Metabolism, Excretion‐Drug–Drug Interaction Science Finally Arrived?

4. Phenotyping of Human CYP450 Enzymes by Endobiotics: Current Knowledge and Methodological Approaches

5. Plasma extracellular nanovesicle (exosome)‐derived biomarkers for drug metabolism pathways: a novel approach to characterize variability in drug exposure

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