Theoretical consideration of the properties of intestinal flow models on route‐dependent drug removal: Segregated Flow (SFM) vs. Traditional (TM)-Reference-Cited by-同舟云学术

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Theoretical consideration of the properties of intestinal flow models on route‐dependent drug removal: Segregated Flow (SFM) vs. Traditional (TM)

Published:2019-05 Issue:5-6 Volume:40 Page:195-213
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm Drug Dispos

Author:

Noh Keumhan¹,Pang K. Sandy¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, Leslie Dan Faculty of PharmacyUniversity of Toronto Toronto Ontario M5S 3M2 Canada

Funder

National Research Foundation of Korea

University of Toronto

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bdd.2184

Reference57 articles.

1. The oligopeptide transporter (Pept-1) in human intestine: Biology and function

2. Predicting the impact of physiological and biochemical processes on oral drug bioavailability

3. Methodology for development of a physiological model incorporating CYP3A and P-glycoprotein for the prediction of intestinal drug absorption

4. Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver

5. Simulations of the Nonlinear Dose Dependence for Substrates of Influx and Efflux Transporters in the Human Intestine

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