Affiliation:
1. Voxalytic GmbH Rosengarten 3 76228 Karlsruhe Germany
2. Institute of Microstructure Technology Karlsruhe Institute of Technology Hermann‐von‐Helmholtz‐Platz 1 76334 Eggenstein‐Leopoldshafen Germany
Abstract
AbstractUnaided nuclear magnetic resonance (NMR) spectroscopy is considered incapable of distinguishing enantiomers. However, as first derived by A.D. Buckingham, the tensor coupling the electric and magnetic dipoles is space‐dependent, which varies according to the molecular structure, hence, would be different for two enantiomers. Exploiting the odd‐parity coupling tensor, a new variant of a double‐resonant radiofrequency (RF) NMR detector is developed, which is sensitive to both electric and magnetic dipoles. Using the detector, a new method for liquid‐state NMR is developed and elaborated, with which two enantiomers are successfully discriminated.
Funder
Deutsche Forschungsgemeinschaft
FP7 Ideas: European Research Council
Helmholtz-Gemeinschaft