Hydrogel‐Guided, rAAV‐Mediated IGF‐I Overexpression Enables Long‐Term Cartilage Repair and Protection against Perifocal Osteoarthritis in a Large‐Animal Full‐Thickness Chondral Defect Model at One Year In Vivo-Reference-Cited by-同舟云学术

Hydrogel‐Guided, rAAV‐Mediated IGF‐I Overexpression Enables Long‐Term Cartilage Repair and Protection against Perifocal Osteoarthritis in a Large‐Animal Full‐Thickness Chondral Defect Model at One Year In Vivo

Published:2021-03-18 Issue:16 Volume:33 Page:2008451
ISSN:0935-9648
Container-title:Advanced Materials
language:en
Short-container-title:Adv. Mater.

Author:

Maihöfer Johanna¹,Madry Henning¹,Rey‐Rico Ana¹,Venkatesan Jagadeesh K.¹,Goebel Lars¹,Schmitt Gertrud¹,Speicher‐Mentges Susanne¹,Cai Xiaoyu¹,Meng Weikun¹,Zurakowski David²,Menger Michael D.³,Laschke Matthias W.³,Cucchiarini Magali¹^ORCID

Affiliation:

1. Center of Experimental Orthopaedics Saarland University and Saarland University Medical Center D‐66421 Homburg/Saar Germany

2. Departments of Anesthesia and Surgery Children's Hospital Boston Harvard Medical School Boston MA 02115 USA

3. Institute for Clinical and Experimental Surgery Saarland University D‐66421 Homburg/Saar Germany

Publisher

Wiley

Subject

Mechanical Engineering,Mechanics of Materials,General Materials Science

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/adma.202008451

Reference58 articles.

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2. Surgical and tissue engineering strategies for articular cartilage and meniscus repair

3. Brief Report: Partial- and Full-Thickness Focal Cartilage Defects Contribute Equally to Development of New Cartilage Damage in Knee Osteoarthritis: The Multicenter Osteoarthritis Study

4. Articular cartilage defects in 1,000 knee arthroscopies

5. Bone Marrow Aspirate Concentrate-Enhanced Marrow Stimulation of Chondral Defects

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