Inhaled mRNA Nanoformulation with Biogenic Ribosomal Protein Reverses Established Pulmonary Fibrosis in a Bleomycin‐Induced Murine Model

Author:

Zhang Rui1,Jing Weiqiang2,Chen Chen1,Zhang Shengchang1,Abdalla Mohnad1,Sun Peng3,Wang Ganyu2,You Wenjie4,Yang Zhenmei1,Zhang Jing1,Tang Chunwei1,Du Wei1,Liu Ying1,Li Xiaoxun1,Liu Jitian1,You Xiaona1,Hu Huili5,Cai Lei6,Xu Fengbo7,Dong Baixiang7,Liu Minglu8,Qiang Bangming8,Sun Yanhua9,Yu Gongchang10,Wu Jibiao3,Zhao Kun1,Jiang Xinyi1ORCID

Affiliation:

1. NMPA Key Laboratory for Technology Research and Evaluation of Drug Products and Key Laboratory of Chemical Biology (Ministry of Education) Department of Pharmaceutics School of Pharmaceutical Sciences Cheeloo College of Medicine Shandong University Jinan 250012 China

2. Department of Urology Qilu Hospital Cheeloo College of Medicine Shandong University Jinan 250012 China

3. Shandong University of Traditional Chinese Medicine Jinan 250355 China

4. Department of Respiratory and Critical Care Medicine Shandong Provincial Hospital Cheeloo College of Medicine Shandong University Jinan 250021 China

5. Experimental Teratology Ministry of Education and Department of Molecular Medicine and Genetics School of Basic Medical Sciences Cheeloo College of Medicine Shandong University Jinan 250012 China

6. Shandong Provincial Key Laboratory of Biosensors, Biology Institute Qilu University of Technology Jinan 250103 China

7. Yinfeng Biological Group Co., LTD. Jinan 250102 China

8. Bellastem Biotechnology Limited Gaomi 261500 China

9. Shandong Provincial Key Laboratory of Microparticles Drug Delivery Technology Qilu Pharmaceutical Co., LtD Jinan 250100 China

10. Neck‐Shoulder and Lumbocrural Pain Hospital Shandong First Medical University & Shandong Academy of Medical Sciences Jinan 250012 China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Mechanical Engineering,Mechanics of Materials,General Materials Science

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