Affiliation:
1. Department of Breast and Thyroid Surgery Renmin Hospital of Wuhan University No 238 Jiefang Road, Wuchang District Wuhan Hubei 430060 P. R. China
2. Animal Biosafety Level III Laboratory at the Center for Animal Experiment Wuhan University School of Medicine Wuhan Hubei 430000 P. R. China
Abstract
AbstractRapid advancements in materials science and nanotechnology, intertwined with oncology, have positioned photothermal therapy (PTT) as a promising noninvasive treatment strategy for cancer. The breast's superficial anatomical location and aesthetic significance render breast cancer a particularly pertinent candidate for the clinical application of PTT following melanoma. This review comprehensively explores the research conducted on the various types of nanoparticles employed in PTT for breast cancer and elaborates on their specific roles and mechanisms of action. The integration of PTT with existing clinical therapies for breast cancer is scrutinized, underscoring its potential for synergistic outcomes. Additionally, the mechanisms underlying PTT and consequential modifications to the tumor microenvironment after treatment are elaborated from a medical perspective. Future research directions are suggested, with an emphasis on the development of integrative platforms that combine multiple therapeutic approaches and the optimization of nanoparticle synthesis for enhanced treatment efficacy. The goal is to push the boundaries of PTT toward a comprehensive, clinically applicable treatment for breast cancer.
Funder
Renmin Hospital of Wuhan University
Beijing Xisike Clinical Oncology Research Foundation
Fundamental Research Funds for the Central Universities
National Natural Science Foundation of China
Subject
Mechanical Engineering,Mechanics of Materials,General Materials Science
Cited by
3 articles.
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