Affiliation:
1. State Key Laboratory of Radio Frequency Heterogeneous Integration Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronics Engineering Shenzhen University Shenzhen 518060 China
2. School of Biomedical Engineering Shenzhen University Shenzhen 518060 China
3. State Key Laboratory of Radio Frequency Heterogeneous Integration College of Electronics and Information Engineering Shenzhen University Shenzhen 518060 China
4. Department of Biomedical Engineering The Chinese University of Hong Kong Shatin 999077 Hong Kong
5. Department of Bioengineering and COMSET Clemson University Clemson SC 29634 USA
Abstract
AbstractOptical manipulation of various kinds of nanoparticles is vital in biomedical engineering. However, classical optical approaches demand higher laser power and are constrained by diffraction limits, necessitating tailored trapping schemes for specific nanoparticles. They lack a universal and biocompatible tool to manipulate nanoparticles of diverse sizes, charges, and materials. Through precise modulation of diffusiophoresis and thermo‐osmotic flows in the boundary layer of an optothermal‐responsive gold film, highly adaptable optothermal nanotweezers (HAONTs) capable of manipulating a single nanoparticle as small as sub‐10 nm are designed. Additionally, a novel optothermal doughnut‐shaped vortex (DSV) trapping strategy is introduced, enabling a new mode of physical interaction between cells and nanoparticles. Furthermore, this versatile approach allows for the manipulation of nanoparticles in organic, inorganic, and biological forms. It also offers versatile function modes such as trapping, sorting, and assembling of nanoparticles. It is believed that this approach holds the potential to be a valuable tool in fields such as synthetic biology, optofluidics, nanophotonics, and colloidal science.
Funder
National Natural Science Foundation of China
Guangdong Provincial Department of Science and Technology
Natural Science Foundation of Guangdong Province
Key Technologies Research and Development Program
Subject
Mechanical Engineering,Mechanics of Materials,General Materials Science