A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex‐Biased Phenotypes-Reference-Cited by-同舟云学术

A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex‐Biased Phenotypes

Published:2020-01-30 Issue:6 Volume:107 Page:1383-1393
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Etheridge Amy S.¹,Gallins Paul J.²,Jima Dereje²,Broadaway K. Alaine³,Ratain Mark J.⁴,Schuetz Erin⁵,Schadt Eric⁶,Schroder Adrian⁷,Molony Cliona⁸,Zhou Yihui²,Mohlke Karen L.³,Wright Fred A.²,Innocenti Federico¹⁹

Affiliation:

1. Eshelman School of Pharmacy and Center for Pharmacogenomics and Individualized Therapy University of North Carolina at Chapel Hill Chapel Hill North Carolina USA

2. Bioinformatics Research Center North Carolina State University Raleigh North Carolina USA

3. Department of Genetics University of North Carolina at Chapel Hill Chapel Hill North Carolina USA

4. Department of Medicine The University of Chicago Chicago Illinois USA

5. Pharmaceutical Sciences St Jude Children’s Research Hospital Memphis Tennessee USA

6. Department of Genetics and Genomic Sciences Icahn School of Medicine at Mount Sinai New York New York USA

7. Center for Bioinformatics Tübingen (ZBIT) University of Tübingen Tübingen Germany

8. Computation Biomedicine Pfizer, Inc. Boston Massachusetts USA

9. Lineberger Comprehensive Cancer Center University of North Carolina at Chapel Hill Chapel Hill North Carolina USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.1751

Reference41 articles.

1. Heritability and genomics of gene expression in peripheral blood

2. Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue

3. Mechanisms of genetic regulation in gene expression: examples from drug metabolizing enzymes and transporters

4. Liver expression quantitative trait loci: a foundation for pharmacogenomic research

5. Transcriptional Profiling of Human Liver Identifies Sex-Biased Genes Associated with Polygenic Dyslipidemia and Coronary Artery Disease

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