Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid‐twenties-Reference-Cited by-同舟云学术

Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid‐twenties

Published:2023-03-30 Issue:2 Volume:3 Page:
ISSN:2692-9384
Container-title:JCPP Advances
language:en
Short-container-title:JCPP Advances

Author:

Lockhart Celestine¹^ORCID,Bright Joanna¹^ORCID,Ahmadzadeh Yasmin¹^ORCID,Breen Gerome¹²^ORCID,Bristow Shannon¹^ORCID,Boyd Andy³^ORCID,Downs Johnny⁴⁵^ORCID,Hotopf Matthew⁵⁶^ORCID,Palaiologou Elisavet¹^ORCID,Rimfeld Kaili¹⁷^ORCID,Maxwell Jessye¹^ORCID,Malanchini Margherita¹⁸^ORCID,McAdams Tom A.¹⁹^ORCID,McMillan Andrew¹^ORCID,Plomin Robert¹^ORCID,Eley Thalia C.¹²^ORCID

Affiliation:

1. Social, Genetic and Developmental Psychiatry Centre Institute of Psychiatry, Psychology and Neuroscience King's College London Camberwell London UK

2. UK National Institute for Health Research (NIHR) Biomedical Research Centre South London and Maudsley Hospital London UK

3. Population Health Sciences Institute Bristol Medical School University of Bristol Bristol UK

4. Department of Child and Adolescent Psychiatry Institute of Psychiatry, Psychology & Neuroscience King's College London London UK

5. South London and Maudsley NHS Foundation Trust London UK

6. Department of Psychological Medicine Institute of Psychiatry Psychology and Neuroscience King's College London London UK

7. Department of Psychology Royal Holloway University of London Egham Surrey UK

8. Queen Mary University of London London UK

9. Promenta Research Centre University of Oslo Oslo UK

Abstract

AbstractThe Twins Early Development Study (TEDS) is a longitudinal study following a cohort of twins born 1994–1996 in England and Wales. Of the 13,759 families who originally consented to take part, over 10,000 families remain enrolled in the study. The current focus of TEDS is on mental health in the mid‐twenties. Making use of over 25 years of genetically sensitive data, TEDS is uniquely placed to explore the longitudinal genetic and environmental influences on common mental health disorders in early adulthood. This paper outlines recent data collection efforts supporting this work, including a cohort‐wide mental health assessment at age 26 and a multi‐phase Covid‐19 study. It will also provide an update on data linkage efforts and the Children of TEDS (CoTEDS) project.

Funder

Wellcome Trust

Medical Research Council

Royal Society

Publisher

Wiley

Subject

General Medicine

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