Toxicity-dependent feasibility bounds for the escalation with overdose control approach in phase I cancer trials-Reference-Cited by-同舟云学术

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Toxicity-dependent feasibility bounds for the escalation with overdose control approach in phase I cancer trials

Published:2017-03-15 Issue:16 Volume:36 Page:2499-2513
ISSN:0277-6715
Container-title:Statistics in Medicine
language:en
Short-container-title:Statist. Med.

Author:

Wheeler Graham M.¹²^ORCID,Sweeting Michael J.³^ORCID,Mander Adrian P.²^ORCID

Affiliation:

1. Cancer Research UK and UCL Cancer Trials Centre; University College London; U.K.

2. MRC Biostatistics Unit Hub for Trials Methodology Research; Cambridge Institute of Public Health; Cambridge U.K.

3. Cardiovascular Epidemiology Unit; Strangeways Research Laboratory University of Cambridge; U.K.

Funder

UK Medical Research Council

European Research Council

British Heart Foundation

Cambridge National Institute for Health Research Biomedical Research Centre

Publisher

Wiley

Subject

Statistics and Probability,Epidemiology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/sim.7280/fullpdf

Reference37 articles.

1. Dose escalation methods in phase I cancer clinical trials;Le Tourneau;Journal of the National Cancer Institute,2009

2. Cancer phase I clinical trials: efficient dose escalation with overdose control;Babb;Statistics in Medicine,1998

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