Randomized control trial of oral arginine therapy for children with sickle cell anemia hospitalized for pain in Nigeria

Author:

Onalo Richard12,Cooper Peter2,Cilliers Antoinette3,Vorster Barend C.4,Uche Nnebe‐Agumadu1,Oluseyi Oniyangi O.5,Onalo Victoria D.6,Zubairu Yunusa6,Ayodele‐Kehinde Alice U.7,Damilare Oladimeji M.8,Figueroa Janet9,Morris Claudia R.1011ORCID

Affiliation:

1. Department of Paediatrics Faculty of Clinical Sciences, University of Abuja Gwagwalada Nigeria

2. Department of Paediatrics Faculty of Clinical Sciences, University of the Witwatersrand Johannesburg South Africa

3. Department of Paediatrics Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand Johannesburg South Africa

4. Centre for Human Metabolomics North West University Potchefstroom South Africa

5. Department of Pediatrics National Hospital Abuja Nigeria

6. Emergency Paediatric Pharmacy University of Abuja Teaching Hospital Gwagwalada Nigeria

7. Department of Pharmacy University of Abuja Teaching Hospital Gwagwalada Nigeria

8. Independent Consultant Abuja Nigeria

9. Department of Pediatrics Biostatistical Core, Emory University School of Medicine Atlanta Georgia USA

10. Division of Pediatric Emergency Medicine, Department of Pediatrics Emory University School of Medicine Atlanta Georgia USA

11. Childrenʼs Healthcare of Atlanta Atlanta Georgia USA

Funder

National Center for Complementary and Integrative Health

Publisher

Wiley

Subject

Hematology

Reference45 articles.

1. Global distribution of the sickle cell gene and geographical confirmation of the malaria hypothesis

2. Centers for Disease Prevention and Control. Centers for Disease Prevention and Control Web site.https://healthcaretrends.co/nigeria-highest-rates-sickle-cell-disease-world/. Accessed October 31 2020.

3. A global perspective on sickle cell disease

4. Sickle Cell Disease in Africa

5. Sickle cell disease child mortality ‐ a silent epidemic in Nigeria: issues in political economy;Muoghalu C;Blood Res Transfus J.,2018

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