Assessing vaccine durability in randomized trials following placebo crossover

Author:

Fintzi Jonathan1ORCID,Follmann Dean1ORCID

Affiliation:

1. Biostatistics Research Branch National Institute of Allergy and Infectious Diseases Bethesda 5601 Maryland USA

Publisher

Wiley

Subject

Statistics and Probability,Epidemiology

Reference25 articles.

1. SARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates

2. Waning Antibody Responses in Asymptomatic and Symptomatic SARS-CoV-2 Infection

3. ModernaA phase 3 randomized stratified observer‐blind placebo‐controlled study to evaluate the efficacy safety and immunogenicity of mRNA‐1273 SARS‐CoV‐2 vaccine in adults aged 18 years and older;2020. https://www.modernatx.com/sites/default/files/mRNA‐1273‐P301‐Protocol.pdf. Accessed November 17 2020.

4. Placebo‐controlled trials of covid‐19 vaccines–why we still need them;World Health Organization;N Engl J Med,2020

5. COVID-19 vaccine trial ethics once we have efficacious vaccines

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