Quantitative determination of six steroid alkaloids by sensitive hydrophilic interaction liquid chromatography electrospray ionization mass spectrometry and its application to pharmacokinetic study in rats

Author:

Chen Jianbo1ORCID,Chen Lixue2,Li Meijia1,Sun Yinshi1

Affiliation:

1. Institute of Special Wild Economic Animals and Plants; Chinese Academy of Agriculture Sciences; Changchun People's Republic of China

2. College of Traditional Chinese Medicinal Material; Jilin Agricultural University; Changchun Jilin People's Republic of China

Funder

The Agricultural Science and Technology Innovation Program

Central Public-interest Scientific Institution Basal Research Fund

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference18 articles.

1. Herbal medicines and perioperative care;Ang-Lee;Journal of the American Medical Directors Association,2001

2. Simultaneous determination of active xanthone glycosides, timosaponins and alkaloids in rat plasma after oral administration of Zi-Shen Pill extract for the pharmacokinetic study by liquid chromatography-tandem mass spectrometry;Cai;Journal of Chromatography B,2010

3. Determination of veratramine in crude dried and processed roots and rhizomes of Veratrum nigrum L. by HPLC;Cong;Journal of Henan University Medicine Science,2008

4. Alkaloid profiling of crude and processed Veratrum nigrum L. through simultaneous determination of ten steroidal alkaloids by HPLC-ELSD;Cong;Journal of Pharmaceutical and Biomedical Analysis,2008

5. A preliminary assessment of the toxic and mutagenic potential of steroidal alkaloids in transgenic mice;Crawford;Food and Chemical Toxicology,1995

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