Telomerase reverse transcriptase promoter alterations across cancer types as detected by next-generation sequencing: A clinical and molecular analysis of 423 patients

Author:

Schwaederle Maria1,Krishnamurthy Nithya1ORCID,Daniels Gregory A.1,Piccioni David E.1ORCID,Kesari Santosh2,Fanta Paul T.1,Schwab Richard B.1,Patel Sandip P.1,Parker Barbara A.1,Kurzrock Razelle1

Affiliation:

1. Center for Personalized Cancer Therapy and Division of Hematology and Oncology, Moores Cancer Center at UC San Diego Health; La Jolla California

2. Department of Translational Neuro-Oncology and Neurotherapeutics; John Wayne Cancer Institute and Pacific Neuroscience Institute at Providence Saint John's Health Center; Santa Monica California

Funder

National Cancer Institute

Joan and Irwin Jacobs

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference43 articles.

1. Hallmarks of cancer: the next generation;Hanahan;Cell.,2011

2. Telomerase activity associated with acquisition of malignancy in human colorectal cancer;Chadeneau;Cancer Res.,1995

3. Telomerase, cell immortality, and cancer;Harley;Cold Spring Harb Symp Quant Biol.,1994

4. Loss of telomeric DNA during aging may predispose cells to cancer (review);Shay;Int J Oncol.,1993

5. Role of telomeres and telomerase in cancer;Shay;Semin Cancer Biol.,2011

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