Separation of a BMS drug candidate and acyl glucuronide from seven glucuronide positional isomers in rat plasma via high-performance liquid chromatography with tandem mass spectrometric detection-Reference-Cited by-同舟云学术

Separation of a BMS drug candidate and acyl glucuronide from seven glucuronide positional isomers in rat plasma via high-performance liquid chromatography with tandem mass spectrometric detection

Published:2006-06-15 Issue:11 Volume:20 Page:1776-1786
ISSN:0951-4198
Container-title:Rapid Communications in Mass Spectrometry
language:en
Short-container-title:Rapid Commun. Mass Spectrom.

Author:

Xue Y.-J.,Simmons Neal J.,Liu Jane,Unger Steve E.,Anderson Danielle F.,Jenkins Rand G.

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference23 articles.

1. Acyl glucuronide reactivity in perspective: biological consequences

2. Acyl Glucuronide Drug Metabolites: Toxicological and Analytical Implications

3. Simultaneous determination of SU5416 and its phase I and phase II metabolites in rat and dog plasma by LC/MS/MS

4. Gemfibrozil and its oxidative metabolites: quantification of aglycones, acyl glucuronides, and covalent adducts in samples from preclinical and clinical kinetic studies

5. Simultaneous determination of zomepirac and its major metabolite zomepirac glucuronide in human plasma and urine

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