Amiodarone triggered Kounis syndrome complicated by refractory cardiac arrest rescued with VA‐ECMO

Author:

Soriano Marc1ORCID,Sionis Alessandro1,Rodríguez Enrique1,Bonet Ana1,Soto Lorena2ORCID,Tauron Manel3,Belmar David1,Arakama Sabiñe1,Mayol Josep1,Rodríguez Laura1

Affiliation:

1. Cardiology Department Hospital de la Santa Creu i Sant Pau Barcelona Spain

2. Allergology Unit Hospital de la Santa Creu i Sant Pau Barcelona Spain

3. Cardiac Surgery Unit Hospital de la Santa Creu i Sant Pau Barcelona Spain

Abstract

Key Clinical MessageAn interesting case that shows an infrequent cause of cardiorespiratory arrest such as coronary vasospasm due to intravenous amiodarone induced Kounis syndrome. It highlights the usefulness of circulatory support with ECMO in the scenario of CPR.AbstractA patient with atrial fibrillation was admitted for an elective electrical cardioversion. He was given an amiodarone bolus that triggered Kounis syndrome with cardiac arrest due to vasospasm requiring emergency coronary angiography with infusion of nitroglycerin. Due to following refractory shock and severe refractory hypoxemia required mechanical circulatory support with ECMO and inhaled nitric oxide with favorable evolution. Allergy to amiodarone was later confirmed.

Publisher

Wiley

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1. Multiple drugs;Reactions Weekly;2024-06-08

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