Parent decision-making around the genetic testing of children for germlineTP53mutations

Author:

Alderfer Melissa A.12,Zelley Kristin1,Lindell Robert B.1,Novokmet Ana3,Mai Phuong L.4,Garber Judy E.5,Nathan Deepika6,Scollon Sarah7,Chun Nicolette M.8,Patenaude Andrea F.9,Ford James M.810,Plon Sharon E.711,Schiffman Joshua D.612,Diller Lisa R.13,Savage Sharon A.4,Malkin David314,Ford Carol A.215,Nichols Kim E.12

Affiliation:

1. Division of Oncology, The Children's Hospital of Philadelphia; Philadelphia Pennsylvania

2. Department of Pediatrics, Perelman School of Medicine; University of Pennsylvania; Philadelphia Pennsylvania

3. Division of Hematology/Oncology; The Hospital for Sick Children; Toronto Ontario Canada

4. Division of Cancer Epidemiology & Genetics, the National Cancer Institute; Bethesda Maryland

5. Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute & Department of Medicine, Harvard Medical School; Boston Massachusetts

6. High Risk Cancer Clinic, Huntsman Cancer Institute & Department of Pediatrics, University of Utah; Salt Lake City Utah

7. Cancer Genetics & Genomic Program, Texas Children's Cancer & Hematology Centers; Houston Texas

8. Cancer Genetics Program, Stanford University Medical Center; Stanford California

9. Division of Pediatric Oncology, Dana Farber Cancer Institute & Department of Psychiatry, Harvard Medical School; Boston Massachusetts

10. Departments of Medicine & Genetics, Stanford University School of Medicine; Stanford California

11. Departments of Pediatrics & Molecular and Human Genetics, Baylor College of Medicine; Houston Texas

12. Department of Pediatrics, University of Utah; Salt Lake City Utah

13. Childhood Cancer Survivor Program, Dana Farber Cancer Institute & Department of Pediatrics, Harvard Medical School; Boston Massachusetts

14. Department of Pediatrics, University of Toronto; Toronto Canada

15. Division of Adolescent Medicine, The Children's Hospital of Philadelphia; Philadelphia Pennsylvania

Funder

Alex's Lemonade Stand Foundation for Childhood Cancer

Center for Childhood Cancer Research, The Children's Hospital of Philadelphia

Center for the Integration of Genetic Healthcare Technologies, University of Pennsylvania

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference14 articles.

1. Update on pediatric cancer predisposition syndromes;Schiffman;Pediatr Blood Cancer,2013

2. P53 germline mutations in childhood cancers and cancer risk for carrier individuals;Chompret;Br J Cancer,2000

3. American Society of Clinical Oncology policy statement update: genetic testing for cancer susceptibility;American Society of Clinical Oncology;J Clin Oncol,2003

4. American Academy of Pediatrics Policy Statement: ethical and policy issues in genetic testing and screening of children;Committee on Bioethics, Committee on Genetics and the American College of Medical Genetics and Genomics Social, Ethical and Legal Issues Committee;Pediatrics,2013

5. Ethical issues in presymptomatic genetic testing for minors: a dilemma in Li-Fraumeni syndrome;Fresneau;J Genet Couns,2013

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