The reversible P2Y12antagonist ACT-246475 causes significantly less blood loss than ticagrelor at equivalent antithrombotic efficacy in rat-Reference-Cited by-同舟云学术

The reversible P2Y12antagonist ACT-246475 causes significantly less blood loss than ticagrelor at equivalent antithrombotic efficacy in rat

Published:2017-08-13 Issue:5 Volume:5 Page:e00338
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacol Res Perspect

Author:

Rey Markus¹^ORCID,Kramberg Markus¹,Hess Patrick¹,Morrison Keith¹,Ernst Roland¹,Haag Franck¹,Weber Edgar¹,Clozel Martine¹,Baumann Martine¹,Caroff Eva¹,Hubler Francis¹,Riederer Markus A.¹,Steiner Beat¹

Affiliation:

1. Idorsia Pharmaceuticals Ltd.; Hegenheimermattweg 91 Allschwil CH-4123 Switzerland

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

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4. Thienopyridines, but not elinogrel, result in off-target effects at the vessel wall that contribute to bleeding;Andre;J Pharmacol Exp Ther,2011

5. ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction-executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999 Guidelines for the Management of Patients With Acute Myocardial Infarction);Antman;Circulation,2004

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