Lysosome and Inflammatory Defects in GBA1 ‐Mutant Astrocytes Are Normalized by LRRK2 Inhibition-Reference-Cited by-同舟云学术

Lysosome and Inflammatory Defects in GBA1 ‐Mutant Astrocytes Are Normalized by LRRK2 Inhibition

Published:2020-02-08 Issue:5 Volume:35 Page:760-773
ISSN:0885-3185
Container-title:Movement Disorders
language:en
Short-container-title:Mov Disord

Author:

Sanyal Anwesha¹,DeAndrade Mark P.¹,Novis Hailey S.¹,Lin Steven¹,Chang Jianjun²,Lengacher Nathalie³,Tomlinson Julianna J.³,Tansey Malú G.⁴,LaVoie Matthew J.¹

Affiliation:

1. Ann Romney Center for Neurological DiseasesBrigham and Women's Hospital and Harvard Medical School Boston Massachusetts USA

2. Department of PhysiologyEmory University School of Medicine Atlanta Georgia USA

3. Program in Neuroscience, Ottawa Hospital Research Institute, University of Ottawa Brain and Mind Research Institute Ottawa Ontario Canada

4. Department of Neuroscience and Center for Translational Research in Neurodegenerative DiseaseNorman Fixel Institute for Neurological Diseases, University of Florida College of Medicine Gainesville Florida USA

Funder

American Parkinson Disease Association

Michael J. Fox Foundation for Parkinson's Research

National Institute of Neurological Disorders and Stroke

Publisher

Wiley

Subject

Clinical Neurology,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/mds.27994

Reference95 articles.

1. Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease