Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors

Author:

Wang Dennis12,Pham Nhu-An1,Tong Jiefei3,Sakashita Shingo14,Allo Ghassan14,Kim Lucia14,Yanagawa Naoki14,Raghavan Vibha1,Wei Yuhong3,To Christine1,Trinh Quang M.5,Starmans Maud H.W.5,Chan-Seng-Yue Michelle A.5,Chadwick Dianne1,Li Lei3,Zhu Chang-Qi1,Liu Ni1,Li Ming1,Lee Sharon1,Ignatchenko Vladimir1,Strumpf Dan1,Taylor Paul3,Moghal Nadeem16,Liu Geoffrey167,Boutros Paul C.468,Kislinger Thomas16,Pintilie Melania1,Jurisica Igor169,Shepherd Frances A.17,McPherson John D.46,Muthuswamy Lakshmi146,Moran Michael F.310,Tsao Ming-Sound146

Affiliation:

1. Princess Margaret Cancer Centre, University Health Network; Toronto ON Canada

2. Sheffield Institute of Translational Neuroscience, University of Sheffield; Sheffield UK S1O 2HQ

3. Program in Molecular Structure and Function; Hospital for Sick Children; Toronto ON Canada

4. Department of Laboratory Medicine and Pathobiology; University of Toronto; Toronto ON Canada

5. Ontario Institute of Cancer Research; Toronto ON Canada

6. Department of Medical Biophysics; University of Toronto; Toronto ON Canada

7. Department of Medicine; University of Toronto; Toronto ON Canada

8. Department of Pharmacology and Toxicology; University of Toronto; Toronto ON Canada

9. Department of Computer Science; University of Toronto; Toronto ON Canada

10. Molecular Genetics, University of Toronto; Toronto ON Canada

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference50 articles.

1. Ferlay J Soerjomataram I Ervik M Dikshit R Eser S Mathers C Rebelo M Parkin DM Forman D Bray F. http://globocaniarcfr , accessed on 13/12/2013 2013

2. Comprehensive genomic characterization of squamous cell lung cancers;Cancer Genome Atlas Research N;Nature,2012

3. Comprehensive molecular profiling of lung adenocarcinoma;Cancer Genome Atlas Research N.;Nature,2014

4. Somatic mutations of signaling genes in non-small-cell lung cancer;Sanders;Cancer Genet Cytogenet,2010

5. Systematic identification of genomic markers of drug sensitivity in cancer cells;Garnett;Nature,2012

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