Classification of high‐grade cervical intraepithelial neoplasia by p16 ink4a , Ki‐67, HPV E4 and FAM19A4 / miR124 ‐2 methylation status demonstrates considerable heterogeneity with potential consequences for management

Author:

Vink Frederique J.1ORCID,Dick Stèfanie1ORCID,Heideman Daniëlle A. M.1ORCID,De Strooper Lise M. A.1,Steenbergen Renske D. M.1ORCID,Lissenberg‐Witte Birgit I.2ORCID,Floore Arno3,Bonde Jesper H.4ORCID,Oštrbenk Valenčak Anja5,Poljak Mario5ORCID,Petry Karl U.6ORCID,Hillemanns Peter7ORCID,Trommel Nienke E.8ORCID,Berkhof Johannes2,Bleeker Maaike C. G.1ORCID,Meijer Chris J. L. M.1ORCID,

Affiliation:

1. Department of Pathology Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam Amsterdam The Netherlands

2. Department of Epidemiology and Data Science Amsterdam UMC, Vrije Universiteit Amsterdam Amsterdam The Netherlands

3. Self‐screen B.V. Amsterdam The Netherlands

4. Molecular Pathology Laboratory, Department of Pathology Hvidovre Hospital Hvidovre Denmark

5. Institute of Microbiology and Immunology, Faculty of Medicine University of Ljubljana Ljubljana Slovenia

6. Department of Gynecologic Oncology Klinikum Wolfsburg Wolfsburg Germany

7. Department of Obstetrics and Gynaecology Hannover Medical School Hannover Germany

8. Antoni van Leeuwenhoek, Netherlands Cancer Institute, Department of Gynecologic Oncology Centre of Gynecologic Oncology Amsterdam Amsterdam The Netherlands

Funder

KWF Kankerbestrijding

Publisher

Wiley

Subject

Cancer Research,Oncology

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