Toll‐like receptor 9 protects non‐immune cells from stress by modulating mitochondrial ATP synthesis through the inhibition of SERCA 2

Author:

Shintani Yasunori12,Drexler Hannes CA3,Kioka Hidetaka4,Terracciano Cesare MN5,Coppen Steven R1,Imamura Hiromi6,Akao Masaharu7,Nakai Junichi8,Wheeler Ann P9,Higo Shuichiro4,Nakayama Hiroyuki10,Takashima Seiji24,Yashiro Kenta1,Suzuki Ken1

Affiliation:

1. William Harvey Research Institute Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK

2. Department of Medical Biochemistry Osaka University Graduate School of Medicine Suita Japan

3. Bioanalytical Mass Spectrometry Max Planck Institute for Molecular Biomedicine Muenster Germany

4. Department of Cardiovascular Medicine Osaka University Graduate School of Medicine Suita Japan

5. Laboratory of Myocardial Electrophysiology Imperial Centre for Translational and Experimental Medicine Imperial College London National Heart & Lung Institute Hammersmith Campus London UK

6. The Hakubi Center & Graduate School of Biostudies Faculty of Medicine Campus Kyoto University Science Frontier Laboratory building Room 305 Kyoto Japan

7. Department of Cardiology National Hospital Organization Kyoto Medical Center Kyoto Japan

8. Saitama University Brain Science Institute Saitama City Japan

9. Blizard Advanced Light Microscopy Facility Blizard Institute Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK

10. Laboratory of Clinical Science and Biomedicine Osaka University Graduate School of Pharmaceutical Sciences Osaka Japan

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

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