An order restricted multi‐arm multi‐stage clinical trial design
Author:
Affiliation:
1. MRC Biostatistics Unit University of Cambridge Cambridge UK
2. Department of Mathematics and Statistics Lancaster University Lancaster UK
Funder
National Institute for Health Research
NIHR Cambridge Biomedical Research Centre
Medical Research Council
Publisher
Wiley
Subject
Statistics and Probability,Epidemiology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/sim.9314
Reference26 articles.
1. Innovation in the pharmaceutical industry: New estimates of R&D costs
2. Sequential designs for phase III clinical trials incorporating treatment selection
3. A generalized Dunnett test for multi-arm multi-stage clinical studies with treatment selection
4. Combining different phases in the development of medical treatments within a single trial
5. Multi-arm clinical trials with treatment selection: what can be gained and at what price?
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2. Determining the minimum duration of treatment in tuberculosis: An order restricted non‐inferiority trial design;Pharmaceutical Statistics;2023-07-06
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