New laboratory evidence for the association between endothelial dysfunction and COVID‐19 disease progression

Author:

Liu Nan12,Long Hui3,Sun Jianhua12,Li Huan3,He Yunting4,Wang Qiang5ORCID,Pan Kai6,Tong Yongliang12,Wang Bingshun4,Wu Qingming35ORCID,Gong Likun127

Affiliation:

1. School of Pharmacy University of Chinese Academy of Sciences Beijing China

2. Center for Drug Safety Evaluation and Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai China

3. Medical College, Tianyou Hospital Wuhan University of Science and Technology Wuhan China

4. Department of Biostatistics, Clinical Research Institute Shanghai Jiao Tong University School of Medicine Shanghai China

5. Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Institute of Infection, Immunology and Tumor Microenvironment, Medical College Wuhan University of Science and Technology Wuhan China

6. Institute of Health Inspection and Testing, Division of Viral Diseases Hubei Provincial Center for Disease Control and Prevention Wuhan China

7. Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica Chinese Academy of Sciences Zhongshan China

Publisher

Wiley

Subject

Infectious Diseases,Virology

Reference41 articles.

1. Emergence of SARS-CoV-2 B.1.1.7 Lineage — United States, December 29, 2020–January 12, 2021

2. European Centre for Disease Prevention and Control. Threat assessment brief: emergence of SARS‐CoV‐2 B.1.617 variants in India and situation in the EU/EEA. Accessed May 11  2021.https://www.ecdc.europa.eu/en/publications-data/threat-assessment-emergence-sars-cov-2-b1617-variants

3. Emergence of a Highly Fit SARS-CoV-2 Variant

4. SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity

5. SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

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