Multiple cutaneous myxofibrosarcoma on the right arm: Clinicopathological features and differential diagnosis

Abstract

Key Clinical MessageThe clinical presentations and pathological features of low‐grade myxofibrosarcoma can be misleading, frequently resulting in diagnostic errors. An accurate diagnosis requires the application of immunohistochemistry techniques and the discerning diagnostic acumen of experienced pathologists. A 62‐year‐old male patient visited our outpatient clinic with multiple painful and rapidly enlarging subcutaneous nodules on his right forearm. Initially, the condition was misdiagnosed as multiple lipomas. The final pathology revealed characteristics consistent with low‐grade myxofibrosarcoma.