The efficacy and safety of leflunomide in patients with active rheumatoid arthritis: A five-year followup study

Author:

Kalden J. R.,Schattenkirchner M.,Sörensen H.,Emery P.,Deighton C.,Rozman B.,Breedveld F.

Funder

Aventis Pharmaceuticals

Publisher

Wiley

Subject

Pharmacology (medical),Immunology,Rheumatology,Immunology and Allergy

Reference21 articles.

1. Reduction in long-term disability in patients with rheumatoid arthritis by disease-modifying antirheumatic drug-based treatment strategies;Fries;Arthritis Rheum,1996

2. Longterm drug therapy for rheumatoid arthritis in seven rheumatology private practices: II. Second line drugs and prednisone;Pincus;J Rheumatol,1992

3. Adverse drug reactions of DMARDs and DC-ARTs in rheumatoid arthritis;Wolfe;Clin Exp Rheumatol,1997

4. The immunosuppressive metabolite of leflunomide is a potent inhibitor of human dihydroorotate dehydrogenase;Davis;Biochemistry,1996

5. Importance of ribonucleotide availability to proliferating T-lymphocytes from healthy humans: disproportionate expansion of pyrimidine pools and contrasting effects of de novo synthesis inhibitors;Fairbanks;J Biol Chem,1995

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