Chaperonin CCT controls extracellular vesicle production and cell metabolism through kinesin dynamics-Reference-Cited by-同舟云学术

Chaperonin CCT controls extracellular vesicle production and cell metabolism through kinesin dynamics

Published:2023-06 Issue:6 Volume:12 Page:
ISSN:2001-3078
Container-title:Journal of Extracellular Vesicles
language:en
Short-container-title:J of Extracellular Vesicle

Author:

Rojas‐Gómez Amelia¹²^ORCID,Dosil Sara G.¹²^ORCID,Chichón Francisco J.³⁴^ORCID,Fernández‐Gallego Nieves¹²^ORCID,Ferrarini Alessia⁵^ORCID,Calvo Enrique⁵,Calzada‐Fraile Diego²^ORCID,Requena Silvia¹⁶^ORCID,Otón Joaquin⁷⁸^ORCID,Serrano Alvaro²,Tarifa Rocio⁵,Arroyo Montserrat¹,Sorrentino Andrea⁸,Pereiro Eva⁸^ORCID,Vázquez Jesus⁵⁶,Valpuesta José M.⁴^ORCID,Sánchez‐Madrid Francisco¹²⁶^ORCID,Martín‐Cófreces Noa B.¹²⁶^ORCID

Affiliation:

1. Immunology Service Hospital Universitario de la Princesa, UAM, IIS‐IP Madrid Spain

2. Area of Vascular Pathophysiology, Laboratory of Intercellular Communication Fundación Centro Nacional de Investigaciones Cardiovasculares‐Carlos III Madrid Spain

3. Cryoelectron Microscopy Unit Centro Nacional de Biotecnología (CNB‐CSIC) Madrid Spain

4. Department of Macromolecular Structure Centro Nacional de Biotecnología (CNB‐CSIC) Madrid Spain

5. Laboratory of Cardiovascular Proteomics Fundación Centro Nacional de Investigaciones Cardiovasculares‐Carlos III Madrid Spain

6. CIBER de Enfermedades Cardiovasculares (CIBERCV) Madrid Spain

7. Structural Studies Division MRC Laboratory of Molecular Biology Cambridge UK

8. ALBA Synchrotron Light Source Barcelona Spain

Abstract

SUMMARYCCT is required to regulate interorganelle contact sites through kinesin‐1 dynamics, modulating peroxisome and mitochondria activity, and ultimately controlling lipid cell content and metabolism.

Funder

Comunidad de Madrid

Agencia Estatal de Investigación

Publisher

Wiley

Subject

Cell Biology,Histology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jev2.12333

Reference87 articles.

1. p90 Ribosomal S6 Kinase and p70 Ribosomal S6 Kinase Link Phosphorylation of the Eukaryotic Chaperonin Containing TCP-1 to Growth Factor, Insulin, and Nutrient Signaling

2. Fast tomographic reconstruction on multicore computers

3. ECM deposition is driven by caveolin-1–dependent regulation of exosomal biogenesis and cargo sorting

4. Acetylated Microtubules Are Preferentially Bundled Leading to Enhanced Kinesin-1 Motility

5. Adapting Proteostasis for Disease Intervention

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