Prediction of clinical effects of infliximab administered for inflammatory bowel disease based on pharmacokinetic and pharmacodynamic modeling

Author:

Kimura Koji1ORCID,Yoshida Atsushi2,Katagiri Fumihiko1,Takayanagi Risa1,Yamada Yasuhiko1

Affiliation:

1. Department of Clinical Evaluation of Drug Efficacy; School of Pharmacy, Tokyo University of Pharmacy and Life Sciences; 1432-1 Horinouchi Hachioji Tokyo 192-0392 Japan

2. Center for Gastroenterology and Inflammatory Bowel Disease; Ofuna Chuo Hospital; 6-2-24 Ofuna Kamakura Kanagawa 247-0056 Japan

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference47 articles.

1. Inflammatory bowel disease;Abraham;The New England Journal of Medicine,2009

2. Tumor necrosis factor-alpha serum level in assessment of disease activity in inflammatory bowel diseases;Avdagic;Medicinski Glasnik,2013

3. Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study;Best;Gastroenterology,1976

4. Evolution of cytokines and inflammatory biomarkers during infliximab induction therapy and the impact of inflammatory burden on primary response in patients with Crohn's disease;Billiet;Scandinavian Journal of Gastroenterology,2017

5. Clinical and biological consequences of immunization to infliximab in pediatric Crohn's disease;Candon;Clinical Immunology,2006

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