CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis

Author:

Schneider Kai Markus1,Bieghs Veerle1,Heymann Felix1,Hu Wei1,Dreymueller Daniela2,Liao Lijun1,Frissen Mick1,Ludwig Andreas2,Gassler Nikolaus3,Pabst Oliver4,Latz Eicke567,Sellge Gernot1,Penders John8,Tacke Frank1,Trautwein Christian1

Affiliation:

1. Department of Internal Medicine III; University Hospital, RWTH Aachen; Aachen Germany

2. Institute of Pharmacology and Toxicology, Medical Faculty, University Hospital, RWTH Aachen; Aachen Germany

3. Institute of Pathology, University Hospital, RWTH Aachen; Aachen Germany

4. Institute of Molecular Medicine, University Hospital, RWTH Aachen; Aachen Germany

5. Institute of Innate Immunity, University Hospital, University of Bonn; Bonn Germany

6. Department of Medicine; University of Massachusetts Medical School; Worcester MA

7. German Center for Neurodegenerative Diseases; Bonn Germany

8. Department of Medical Microbiology; School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center; Maastricht The Netherlands

Funder

Alexander von Humboldt-Stiftung

Deutsche Forschungsgemeinschaft

Deutsche Krebshilfe

Federal Ministry of Education and Research (ObiHep grant)

Interdisciplinary Centre for Clinical Research (START grant), Faculty of Medicine at the RWTH Aachen University

Publisher

Wiley

Subject

Hepatology

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