Role of Hepatic Drug Transporters in Drug Development
Author:
Affiliation:
1. Mechanistic Safety and Disposition, Platform Technology and Science; GlaxoSmithKline R&D; Shanghai China
2. Projects, Standards & Innovation; Asia Pacific DSAR, Sanofi; Shanghai China
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Reference89 articles.
1. Hepatic and intestinal drug transporters: prediction of pharmacokinetic effects caused by drug-drug interactions and genetic polymorphisms;Yoshida;Annu Rev Pharmacol Toxicol,2013
2. Transporters as a determinant of drug clearance and tissue distribution;Shitara;Eur J Pharm Sci,2006
3. A perspective on efflux transport proteins in the liver;Köck;Clin Pharmacol Ther,2012
4. Membrane transporters in drug development;Giacomini;Nat Rev Drug Discov,2010
5. US Food and Drug Administration http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/ucm292362.pdf
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