Synthesis and biological activity of analogs of the antifungal antibiotic UK‐2A. III. Impact of modifications to the macrocycle isobutyryl ester position

Author:

Owen W John1ORCID,Meyer Kevin G2,Slanec Thomas J1,Meyer Stacy T1,Wang Nick X2,Fitzpatrick Gina M2,Niyaz Noormohamed N2,Nugent Jaime2,Ricks Michael J2,Rogers Richard B2,Yao Chenglin1

Affiliation:

1. Crop Protection Discovery Biology, Corteva Agriscience™ Agriculture Division of DowDuPont Indianapolis IN USA

2. Crop Protection Discovery Chemistry, Corteva Agriscience™ Agriculture Division of DowDuPont Indianapolis IN USA

Publisher

Wiley

Subject

Insect Science,Agronomy and Crop Science,General Medicine

Reference35 articles.

1. UK-2A, B, C and D, Novel Antifungal Antibiotics from Streptomyces sp. 517-02. II. Structural Elucidation.

2. The structures of UK‐1 and UK‐2, novel antibiotics from Streptomyces sp. 517‐02;Hanafi OM;Tennen Yuki Kagobutsu Toronkai Koen Yoshishu,1994

3. UK-2A, B, C and D, Novel Antifungal Antibiotics from Streptomyces sp. 517-02. III. Absolute Configuration of an Antifungal Antibiotic, UK-2A, and Consideration of Its Conformation.

4. UK-2A, B, C and D, Novel Antifungal Antibiotics from Streptomyces sp. 517-02. I. Fermentation, Isolation, and Biological Properties.

5. Antifungal inhibitors of mitochondrial respiration: discovery and prospects for development;Ueki M;Curr Opin Anti‐Infect Invest Drugs,2000

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