The more you test, the more you find: The smallest P -values become increasingly enriched with real findings as more tests are conducted-Reference-Cited by-同舟云学术

The more you test, the more you find: The smallest P -values become increasingly enriched with real findings as more tests are conducted

Published:2017-09-14 Issue:8 Volume:41 Page:726-743
ISSN:0741-0395
Container-title:Genetic Epidemiology
language:en
Short-container-title:Genet. Epidemiol.

Author:

Vsevolozhskaya Olga A.¹^ORCID,Kuo Chia-Ling²,Ruiz Gabriel³,Diatchenko Luda⁴,Zaykin Dmitri V.⁵

Affiliation:

1. Department of Biostatistics; University of Kentucky; Lexington Kentucky United States of America

2. Department of Community Medicine and Heath Care, Institute for Systems Genomics; University of Connecticut Health Center; Farmington Connecticut United States of America

3. Summer Internship Program, National Institute of Environmental Health Sciences; National Institutes of Health; Durham North Carolina USA

4. The Alan Edwards Centre for Research on Pain; McGill University; Montreal Canada

5. National Institute of Environmental Health Sciences; National Institutes of Health; Durham North Carolina USA

Funder

National Institutes of Health

National Institute of Environmental Health Sciences

Publisher

Wiley

Subject

Genetics(clinical),Epidemiology

Reference34 articles.

1. Bollen , K. Cacioppo , J. Kaplan , R. Krosnick , J. Olds , J. 2015 Social, behavioral, and economic sciences perspectives on robust and reliable science. Report of the Subcommittee on Replicability in Science, Advisory Committee to the National Science Foundation Directorate for Social, Behavioral, and Economic Sciences Retrieved from http://www.nsf.gov/sbe/AC_Materials/SBE_Robust_and_Reliable_Research_Report.pdf

2. P-value precision and reproducibility;Boos;American Statistician,2011

3. Replication and P-intervals: P-values predict the future only vaguely, but confidence intervals do much better;Cumming;Perspectives on Psychological Science,2008

4. Selection paradoxes of Bayesian inference;Dawid;Multivariate Analysis and Its Applications,1994

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