An integrative approach to assess X-chromosome inactivation using allele-specific expression with applications to epithelial ovarian cancer

Author:

Larson Nicholas B.1ORCID,Fogarty Zachary C.1,Larson Melissa C.1,Kalli Kimberly R.2,Lawrenson Kate34,Gayther Simon4,Fridley Brooke L.5,Goode Ellen L.6,Winham Stacey J.1ORCID

Affiliation:

1. Division of Biomedical Statistics and Informatics; Department of Health Sciences Research; Mayo Clinic; Rochester Minnesota United States of America

2. Department of Medical Oncology; Mayo Clinic; Rochester Minnesota United States of America

3. Women's Cancer Program; Samuel Oschin Comprehensive Cancer Institute; Cedars-Sinai Medical Center; Los Angeles California United States of America

4. Center for Bioinformatics and Functional Genomics; Samuel Oschin Comprehensive Cancer Institute; Cedars-Sinai Medical Center; Los Angeles California United States of America

5. Department of Biostatistics and Bioinformatics; Moffitt Cancer Center; Tampa Florida United States of America

6. Division of Epidemiology; Department of Health Sciences Research; Mayo Clinic; Rochester Minnesota United States of America

Funder

Office of Research on Women's Health

Fraternal Order of Eagles

National Institutes of Health

National Cancer Institute

Publisher

Wiley

Subject

Genetics(clinical),Epidemiology

Reference50 articles.

1. Derivation of consensus inactivation status for X-linked genes from genome-wide studies;Balaton;Biology of Sex Differences,2015

2. Chromosomes, sex chromatin, and cancer;Barr;Proceedings of the Canadian Cancer Conference,1957

3. Genes that escape from X inactivation;Berletch;Human Genetics,2011

4. DDX3, a potential target for cancer treatment;Bol;Molecular Cancer,2015

5. Association between nonrandom X-chromosome inactivation and BRCA1 mutation in germline DNA of patients with ovarian cancer;Buller;Journal of the National Cancer Institute,1999

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