Affiliation:
1. Department of Pediatrics, Severance Children's Hospital Yonsei University College of Medicine Seoul South Korea
2. Department of Biomedical Systems Informatics Yonsei University College of Medicine Seoul South Korea
3. Institute for Immunology and Immunological Diseases Yonsei University College of Medicine Seoul South Korea
Abstract
AbstractLimited data are available on the impact of the coronavirus disease (COVID‐19) pandemic on encephalitis. Therefore, we evaluated trends in encephalitis in South Korea between 2010 and 2021 using data from the National Health Insurance Service. During the pandemic (February 2020 to 2021), the monthly incidence of encephalitis declined by 0.027 per 100 000 population (95% confidence interval [CI]: −0.055 to 0.001, p = 0.062) compared to that before the pandemic. In subgroup analysis, the estimated coefficient for level change during the pandemic in the 0–4 and 5–9 years age groups were −2.050 (95% CI: −2.972 to −1.128, p < 0.001) and −0.813 (95% CI: −1.399 to −0.227, p = 0.008), respectively. The annual incidence of encephalitis during the pandemic period significantly decreased in the 0–4 and 5–9 years age groups (incidence rate ratio: 0.34 [p = 0.007] and 0.28 [p = 0.024], respectively). The intensive care unit admission rate (39.1% vs. 58.9%, p < 0.001) and cases of death (8.9% vs. 11.1%, p < 0.001) decreased significantly during the pandemic compared to the prepandemic. During the pandemic, the incidence of encephalitis decreased markedly in South Korea, particularly in children aged ≤9 years. In addition, there were changes in the clinical outcome of encephalitis during the COVID‐19 pandemic.
Funder
Ministry of Education
Ministry of Health and Welfare
Ministry of Science and ICT, South Korea
Yonsei University College of Medicine
Subject
Infectious Diseases,Virology
Cited by
1 articles.
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