α1-Antitrypsin in Fibromyalgia: Results of a Randomized, Placebo-Controlled, Double-Blind and Crossover Pilot Trial

Author:

Alegre Cayetano1,Barceló Mireia1,Jardí Rosendo2,Rodríguez-Frias Francisco2,Camprubí Sandra3

Affiliation:

1. Department of Rheumatology; Hospital Universitari Vall d'Hebron; Barcelona; Spain

2. Department of Biochemistry; Hospital Universitari Vall d'Hebron; Barcelona; Spain

3. Clinical Trials and Pharmacovigilance Department; Instituto Grifols, S.A.; Barcelona; Spain

Publisher

Wiley

Subject

Nursing (miscellaneous),Rehabilitation,Physical Therapy, Sports Therapy and Rehabilitation,Orthopedics and Sports Medicine,Chiropractics,Rheumatology

Reference21 articles.

1. Standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency;American Thoracic Society/European Respiratory Society;American Journal of Respiratory and Critical Care Medicine,2003

2. Alpha1-antitrypsin replacement therapy controls fibromyalgia symptoms in 2 patients with PI ZZ alpha1-antitrypsin deficiency;Blanco;Journal of Rheumatology,2004

3. Alpha1-antitrypsin and fibromyalgia: New data in favour of the inflammatory hypothesis of fibromyalgia;Blanco;Medical Hypotheses,2005

4. Estimates of the prevalence and number of fibromyalgia syndrome patients and their alpha-1 antitrypsin phenotypic distribution in ten countries;Blanco;Journal of Musculoskeletal Pain,2007

5. Low plasma levels of monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor-alpha (TNFalpha), and vascular endothelial growth factor (VEGF) in patients with alpha1-antitrypsin deficiency-related fibromyalgia;Blanco;Clinical Rheumatology,2010

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