Aurothiomalate inhibits cyclooxygenase 2, matrix metalloproteinase 3, and interleukin-6 expression in chondrocytes by increasing MAPK phosphatase 1 expression and decreasing p38 phosphorylation: MAPK phosphatase 1 as a novel target for antirheumatic drugs
Author:
Publisher
Wiley
Subject
Pharmacology (medical),Immunology,Rheumatology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/art.27409/fullpdf
Reference45 articles.
1. Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage: influence of nitric oxide;Amin;J Clin Invest,1997
2. Nitric oxide synthase and cyclooxygenases: distribution, regulation, and intervention in arthritis;Amin;Curr Opin Rheumatol,1999
3. The regulation of chondrocyte function by proinflammatory mediators: prostaglandins and nitric oxide;Goldring;Clin Orthop Relat Res,2004
4. Regulation and Function of Prostaglandin Synthase 2/Cyclooxygenase II
5. p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes;Dean;J Biol Chem,1999
Cited by 57 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF‑κB and MAPK signalling transduction through integrin αVβ3;International Journal of Molecular Medicine;2023-08-29
2. MKP-1 Deficiency Exacerbates Skin Fibrosis in a Mouse Model of Scleroderma;International Journal of Molecular Sciences;2023-02-28
3. Dexamethasone Attenuates the Expression of MMP-13 in Chondrocytes through MKP-1;International Journal of Molecular Sciences;2022-03-31
4. Protein tyrosine phosphatases in skeletal development and diseases;Bone Research;2022-01-28
5. DUSP-1 Induced by PGE2 and PGE1 Attenuates IL-1β-Activated MAPK Signaling, Leading to Suppression of NGF Expression in Human Intervertebral Disc Cells;International Journal of Molecular Sciences;2021-12-29
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3