Mechanistic Projection of First-in-Human Dose for Bispecific Immunomodulatory P-Cadherin LP-DART: An Integrated PK/PD Modeling Approach-Reference-Cited by-同舟云学术

Mechanistic Projection of First-in-Human Dose for Bispecific Immunomodulatory P-Cadherin LP-DART: An Integrated PK/PD Modeling Approach

Author:

Chen X¹,Haddish-Berhane N²³,Moore P⁴,Clark T²,Yang Y⁴,Li H⁴,Xuan D⁵,Barton HA²,Betts AM²,Barletta F⁶

Affiliation:

1. Pharmacokinetics, Dynamics and Metabolism; Pfizer; Cambridge Massachusetts USA

2. Pharmacokinetics, Dynamics and Metabolism; Pfizer; Groton Connecticut USA

3. Current Address: Clinical Pharmacology and Pharmacometrics; Quantitative Sciences Janssen Pharmaceuticals, Spring House, Pennsylvania USA

4. MacroGenics; Rockville; Maryland USA

5. Clinical Pharmacology; Pfizer; San Diego California USA

6. Pharmacokinetics, Dynamics and Metabolism; Pfizer; Pearl River New York USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference28 articles.

1. Monoclonal antibodies in human cancer;Mellstedt;Drugs Today,2003

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