The post-therapeutic effect of rapamycin in mild traumatic brain-injured rats ensuing in the upregulation of autophagy and mitophagy

Author:

Wang Changxing1,Hu Zhiying2,Zou Yang1,Xiang Mingjun3,Jiang Yuting3,Botchway Benson O. A.3,Huo Xue3,Du Xiaoxue3,Fang Marong3ORCID

Affiliation:

1. Department of Orthopedics; The Second Affiliated Hospital of Zhejiang Chinese Medical University; Hangzhou China

2. Department of Obstetrics and Gynecology; Hangzhou Red Cross Hospital; Hangzhou China

3. Institute of Neuroscience; Zhejiang University School of Medicine; Hangzhou 310058 China

Funder

Traditional Chinese Medicine Science and Technology planning project of Zhejiang province

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cell Biology,General Medicine

Reference38 articles.

1. Epidemiology of postconcussion syndrome in pediatric mild traumatic brain injury;Barlow;Pediatrics,2010

2. Sleep deprivation does not affect neuronal susceptibility to mild traumatic brain injury in the rat;Caron;Nat Sci Sleep,2015

3. Acute focal brain damage alters mitochondrial dynamics and autophagy in axotomized neurons;Cavallucci;Cell Death Dis,2014

4. What genetics tells us about the causes and mechanisms of Parkinson's disease;Corti;Physiol Rev,2011

5. Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission;Dagda;J Biol Chem,2009

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