Distal Upper Limb Tremor during Walking in Parkinson's Disease-Reference-Cited by-同舟云学术

Distal Upper Limb Tremor during Walking in Parkinson's Disease

Published:2023-06-22 Issue:8 Volume:10 Page:1198-1202
ISSN:2330-1619
Container-title:Movement Disorders Clinical Practice
language:en
Short-container-title:Movement Disord Clin Pract

Author:

Costanzo Matteo¹^ORCID,Cutrona Carolina¹,Leodori Giorgio¹²^ORCID,De Bartolo Maria Ilenia¹^ORCID,Fabbrini Andrea²,Vivacqua Giorgio³⁴^ORCID,Conte Antonella¹²^ORCID,Fabbrini Giovanni¹²^ORCID,Berardelli Alfredo¹²^ORCID,Belvisi Daniele¹²^ORCID

Affiliation:

1. IRCCS Neuromed Pozzilli Italy

2. Department of Human Neurosciences Sapienza University of Rome Rome Italy

3. Department of Experimental Morphology and Microscopy – Integrated Research Center (PRAAB) – Campus Biomedico University of Rome Rome Italy

4. Department of Anatomical, Histological, Forensic Medicine and Orthopedics Sciences Sapienza University of Rome Rome Italy

Abstract

AbstractBackgroundDistal upper limb tremor during walking (TW) is frequently observed in Parkinson's disease (PD) but its clinical features are unknown.ObjectiveTo characterize the occurrence and the clinical features of TW in comparison to the other types of tremors in PD.MethodsFifty‐one PD patients with rest tremor were evaluated off‐ and on‐treatment. Occurrence, body distribution, severity and latency of TW and of other tremor types were assessed.ResultsTW was present in 78% of the PD patients examined. TW body distribution and severity were similar to those of rest and re‐emergent tremor but different from the postural tremor presented by the same patients. TW latency, observed in 85% of patients, was on average 5.8 s. Dopaminergic treatment significantly improved TW, rest, and re‐emergent tremor severity but left TW latency unaffected.ConclusionsTW is a frequent motor sign in PD and is likely a clinical variant of rest tremor.

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Reference29 articles.

1. Occurrence of resting tremor in Parkinson's disease

2. The clinical and electrophysiological investigation of tremor

3. Are we making progress in the understanding of tremor in Parkinson's disease?

4. Cerebral causes and consequences of parkinsonian resting tremor: a tale of two circuits?

5. Consensus Statement on the classification of tremors. from the task force on tremor of the International Parkinson and Movement Disorder Society