Enhance 4′-epidaunorubicin production of engineeringStreptomyces coeruleorubidusstrains via both knockout of daunorubicin-consuming enzymesdnrXanddnrU, and multiple copies of rate-limiting enzymeaveBIV-Reference-Cited by-同舟云学术

Enhance 4′-epidaunorubicin production of engineeringStreptomyces coeruleorubidusstrains via both knockout of daunorubicin-consuming enzymesdnrXanddnrU, and multiple copies of rate-limiting enzymeaveBIV

Published:2018-07-12 Issue:12 Volume:93 Page:3613-3618
ISSN:0268-2575
Container-title:Journal of Chemical Technology & Biotechnology
language:en
Short-container-title:J. Chem. Technol. Biotechnol.

Author:

Shao Lei¹²,Chen Ji-Ye²,Zi Jia-Chen³,Chen Dai-Jie⁴^ORCID

Affiliation:

1. Shanghai University of Medicine & Health Sciences; Shanghai PR China

2. State Key Lab of New Drug and Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry; Shanghai PR China

3. College of Pharmacy, Jinan University; Guangzhou PR China

4. School of Pharmacy; Shanghai Jiaotong University; Shanghai PR China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shanghai

Program of Shanghai Subject Chief Scientist

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Pollution,Waste Management and Disposal,Fuel Technology,Renewable Energy, Sustainability and the Environment,General Chemical Engineering,Biotechnology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jctb.5741/fullpdf

Reference21 articles.

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2. Equivalence ratio for Daunorubicin to doxorubicin in relation to late heart failure in survivors of childhood cancer;Feijen;J Clin Oncol,2015

3. 'Daunomycin', a new antibiotic of the rhodomycin group;Marco;Nature,1964

4. Cloning and expression of daunorubicin biosynthesis genes from Streptomyces peucetius and S. peucetius subsp. caesius;Otten;J Bacteriol,1990

5. Biotechnological doxorubicin production: pathway and regulation engineering of strains for enhanced production;Niraula;Appl Microbiol Biotechnol,2010

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