Development of high throughput screening assays and pilot screen for inhibitors of metalloproteases meprin α and β-Reference-Cited by-同舟云学术

Development of high throughput screening assays and pilot screen for inhibitors of metalloproteases meprin α and β

Published:2014-09 Issue:5 Volume:102 Page:396-406
ISSN:0006-3525
Container-title:Biopolymers
language:en
Short-container-title:Biopolymers

Author:

Madoux Franck¹,Tredup Claudia²,Spicer Timothy P.¹,Scampavia Louis¹,Chase Peter S.¹,Hodder Peter S.³,Fields Gregg B.⁴,Becker-Pauly Christoph²,Minond Dmitriy⁴

Affiliation:

1. Lead Identification Division; Translational Research Institute, The Scripps Research Institute; 130 Scripps Way Jupiter, Fl 34987

2. University of Kiel, Institute of Biochemistry, Unit for Degradomics of the Protease Web; Rudolf-Höber-Str.1 24118 Kiel Germany

3. Amgen, Inc. 1 Amgen Center Drive, Newbury Park; CA 91320

4. Torrey Pines Institute for Molecular Studies; 11350 SW Village Parkway Port Saint Lucie FL 34987

Funder

National Institutes of Health

Deutsche Forschungsgemeinschaft

James and Esther King Bio-medical Research Program

Publisher

Wiley

Subject

Organic Chemistry,Biomaterials,Biochemistry,General Medicine,Biophysics

Reference28 articles.

1. Meprins, membrane-bound and secreted astacin metalloproteinases

2. Structure of Homo- and Hetero-oligomeric Meprin Metalloproteases

3. Structural basis for the sheddase function of human meprin metalloproteinase at the plasma membrane

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