Prion-like Aggregation of Mitochondrial Antiviral Signaling Protein in Lupus Patients Is Associated With Increased Levels of Type I Interferon
Author:
Affiliation:
1. Lewis Katz School of Medicine at Temple University; Philadelphia Pennsylvania
2. University of North Carolina at Chapel Hill
Funder
NIH
Alliance for Lupus Research
Publisher
Wiley
Subject
Immunology,Rheumatology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/art.39733/fullpdf
Reference34 articles.
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3. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF 3;Seth;Cell,2005
4. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction;Kawai;Nat Immunol,2005
5. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus;Meylan;Nature,2005
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