Oral IDN-6556, an antiapoptotic caspase inhibitor, may lower aminotransferase activity in patients with chronic hepatitis C-Reference-Cited by-同舟云学术

Oral IDN-6556, an antiapoptotic caspase inhibitor, may lower aminotransferase activity in patients with chronic hepatitis C

Published:2007 Issue:2 Volume:46 Page:324-329
ISSN:0270-9139
Container-title:Hepatology
language:en
Short-container-title:Hepatology

Author:

Pockros Paul J.,Schiff Eugene R.,Shiffman Mitchell L.,McHutchison John G.,Gish Robert G.,Afdhal Nezam H.,Makhviladze Manana,Huyghe Mira,Hecht David,Oltersdorf Tilman,Shapiro David A.

Publisher

Wiley

Subject

Hepatology

Reference20 articles.

1. Cell Death

2. Characterization of IDN-6556 (3-{2-(2-tert-Butyl-phenylaminooxalyl)-amino]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic Acid): a Liver-Targeted Caspase Inhibitor

3. The Caspase Inhibitor IDN-6556 Attenuates Hepatic Injury and Fibrosis in the Bile Duct Ligated Mouse

4. The caspase inhibitor IDN-6556 prevents caspase activation and apoptosis in sinusoidal endothelial cells during liver preservation injury

5. Caspase activation correlates with the degree of inflammatory liver injury in chronic hepatitis C virus infection

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