Membrane‐destabilizing ionizable lipid empowered imaging‐guided siRNA delivery and cancer treatment

Author:

Guo Shuai1,Li Kun1,Hu Bo1,Li Chunhui1,Zhang Mengjie1,Hussain Abid1,Wang Xiaoxia2,Cheng Qiang3,Yang Feng4,Ge Kun5,Zhang Jinchao5,Chang Jin6,Liang Xing‐Jie7ORCID,Weng Yuhua1,Huang Yuanyu1ORCID

Affiliation:

1. School of Life Science, Advanced Research Institute of Multidisciplinary Science, Key Laboratory of Molecular Medicine and Biotherapy, Institute of Engineering Medicine Beijing Institute of Technology Beijing P. R. China

2. Institute of Molecular Medicine, College of Future Technology Peking University Beijing P. R. China

3. Department of Biochemistry Simmons Comprehensive Cancer Center The University of Texas Southwestern Medical Center Dallas Texas USA

4. Howard Hughes Medical Institute, Department of Medicine, School of Medicine University of California, San Diego La Jolla California USA

5. Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Environmental Science, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education Hebei University Baoding P. R. China

6. School of Life Sciences, Tianjin Engineering Center of Micro Nano Biomaterials and Detection Treatment Technology Collaborative Innovation Center of Chemical Science and Engineering, Tianjin University Tianjin P. R. China

7. Chinese Academy of Sciences (CAS) Center for Excellence in Nanoscience and CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety National Center for Nanoscience and Technology Beijing P. R. China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Publisher

Wiley

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