Affiliation:
1. Bio‐Evaluation Center, Korea Research Institute of Bioscience and Biotechnology Cheongju 28116 Republic of Korea
2. Department of Biosystems and Bioengineering, KRIBB School of Biotechnology Korea University of Science and Technology (UST) Daejeon Republic of Korea
Abstract
AbstractCell‐free protein synthesis (CFPS) system is an innovative technology with a wide range of potential applications that could challenge current thinking and provide solutions to environmental and health issues. CFPS system has been demonstrated to be a successful way of producing biomolecules in a variety of applications, including the biomedical industry. Although there are still obstacles to overcome, its ease of use, versatility, and capacity for integration with other technologies open the door for it to continue serving as a vital instrument in synthetic biology research and industry. In this review, we mainly focus on the cell‐free based platform for various product productions. Moreover, the challenges in the bio‐therapeutic aspect using cell‐free systems and their future prospective for the improvement and sustainability of the cell free systems.
Subject
Process Chemistry and Technology,Drug Discovery,Applied Microbiology and Biotechnology,Biomedical Engineering,Molecular Medicine,General Medicine,Bioengineering,Biotechnology