Methylation-independent CHFR expression is a potential biomarker affecting prognosis in acute myeloid leukemia

Author:

Zhou Jing-Dong12ORCID,Zhang Ting-Juan12ORCID,Li Xi-Xi12,Ma Ji-Chun23,Guo Hong23,Wen Xiang-Mei23,Yao Dong-Ming23,Zhang Wei12,Lin Jiang23ORCID,Qian Jun12ORCID

Affiliation:

1. Department of Hematology; Affiliated People's Hospital of Jiangsu University; Zhenjiang Jiangsu P.R. China

2. The Key Lab of Precision Diagnosis and Treatment of Zhenjiang City; Zhenjiang Jiangsu P.R. China

3. Laboratory Center; Affiliated People's Hospital of Jiangsu University; Zhenjiang Jiangsu P.R. China

Funder

Social Development Foundation of Zhenjiang

China Postdoctoral Science Foundation

Postgraduate Research & Practice Innovation Program of Jiangsu Province

2016 Medical Science and Technology Development Fund of Jiangsu University

Special Funds of “Ke Jiao Qiang Wei” Project of Jiangsu Province

National Natural Science Foundation of China

Six Talent Peaks Project in Jiangsu Province

333 Project of Jiangsu Province

Key Medical Talent Program of Zhenjiang City

Innovative Team of Jiangsu Province

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Reference15 articles.

1. Frequent hypermethylation of the 5' CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer;Corn;Carcinogenesis,2003

2. Emerging evidence for CHFR as a cancer biomarker: From tumor biology to precision medicine;Derks;Cancer Metastasis Reviews,2014

3. Acute myeloid leukaemia;Estey;Lancet,2006

4. CHFR hypermethylation, a frequent event in acute myeloid leukemia, is independently associated with an adverse outcome;Gao;Genes Chromosomes Cancer,2016

5. Diagnostic and prognostic value of cytogenetics in acute myeloid leukemia;Grimwade;Hematology-Oncology Clinics Of North America,2011

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