Interaction effects on cytochrome P450 bothin vitroandin vivostudies by two major bioactive xanthones fromHalenia ellipticaD. Don

Author:

Feng Ru1,Tan Xiang-Shan1,Wen Bao-Ying1,Shou Jia-Wen1,Fu Jie1,He Chi-Yu1,Zhao Zhen-Xiong1,Li Xiao-Yang1,Zhu Hui-Xin1,Zhu Ping1,Shi Jian-Gong1,Che Chun-Tao2,Yeung John H. K.3,Zhang Xian-Feng4,Wang Yan1

Affiliation:

1. State Key Laboratory of Bioactive Substances and Functions of Natural Medicines; Institute of Materia Medica, Chinese Academy of Medical Sciences; Beijing China

2. Department of Medicinal Chemistry & Pharmacognosy (MC 781) UIC College of Pharmacy; Chicago USA

3. School of Biomedical Sciences, Faculty of Medicine; The Chinese University of Hong Kong; Hong Kong, China

4. Department of Neurosurgery; First Hospital, Jilin University; Changchun China

Funder

National 863 Program of China

National Mega-project for Innovative Drugs

National Natural Science Foundation of China

Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference35 articles.

1. Effect of entecavir combined with Yiganjian in the treatment of chronic hepatitis B;Ao;Inner Mongolia Medical Journal,2011

2. The effects of Danshen (Salvia miltiorrhiza) on warfarin pharmacodynamics and pharmacokinetics of warfarin enantiomers in rats;Chan;Journal of Pharmacy and Pharmacology,1995

3. Interaction between warfarin and danshen (Salvia miltiorrhiza);Chan;Annals of Pharmacotherapy,2001

4. Mechanisms of vasorelaxation of thoracic aorta caused by xanthone;Cheng;European Journal of Pharmacology,1997

5. The xanthones Gentiacaulein and Gentiakochianin are responsible for the vasodilator action of the roots of Gentiana kochiana;Chericoni;Planta Medica,2003

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