Imidazo[1,2,4]triazolone and fused imidazo[1,2,4]triazolone derivatives: Synthesis, in vitro anticancer screening, <scp>CDK2</scp> inhibitory activity, and molecular modeling studies-Reference-Cited by-同舟云学术

Imidazo[1,2,4]triazolone and fused imidazo[1,2,4]triazolone derivatives: Synthesis, in vitro anticancer screening, CDK2 inhibitory activity, and molecular modeling studies

Published:2022-08-26 Issue:12 Volume:59 Page:2207-2224
ISSN:0022-152X
Container-title:Journal of Heterocyclic Chemistry
language:en
Short-container-title:Journal of Heterocyclic Chem

Author:

El Rabeeb Shaimaa I.¹,El Deeb Moshira A.¹²^ORCID,Sarg Marwa T.¹,Hassan Aisha Y.³

Affiliation:

1. Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy (Girls) Al‐Azhar University Cairo Egypt

2. Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy Modern University for Technology & Information Cairo Egypt

3. Organic Chemistry Department, Faculty of Science (Girls) Al‐Azhar University Cairo Egypt

Publisher

Wiley

Subject

Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jhet.4552

Reference57 articles.

1. Eco-friendly sequential one-pot synthesis, molecular docking, and anticancer evaluation of arylidene-hydrazinyl-thiazole derivatives as CDK2 inhibitors

2. A novel anthracene derivative, MHY412, induces apoptosis in doxorubicin-resistant MCF-7/Adr human breast cancer cells through cell cycle arrest and downregulation of P-glycoprotein expression

3. Synthetic curcumin derivative DK1 possessed G2/M arrest and induced apoptosis through accumulation of intracellular ROS in MCF-7 breast cancer cells

4. Design and green synthesis of novel quinolinone derivatives of potential anti-breast cancer activity against MCF-7 cell line targeting multi-receptor tyrosine kinases

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